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KMID : 0870420040080010054
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Korean Journal of Hepato-Biliary-Pancreatic Surgery
2004 Volume.8 No. 1 p.54 ~ p.59
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Sarcomatoid Cholangiocarcinoma of the Liver, a case study
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Kim Kyu-Sung
Park Jong-Hoon
Sohn Kyung-Rak
Shin Dong-Gun
Bae Byung-Jo
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Abstract
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A 71 year-old man with persistent fever, right pleuritic pain and discomfort for 2 months was referred to hospital. An imaging study using ultiasonography, computed tomography and magnetic resonance imaging showed a huge hepatic mass, which was revealed to be a sarcoma-like mass of the right lobe of the liver. On laparotomy, 5, 6 and 7 segmentectomies were performed: The tumor was 18 x 16 x 15 an in size. On cross secfion the tumor was a yellowishfarining,. diffusely soft, friable and clearly demarcated mass. Mlc roscopically, the tumor cells were contained in the sarcomatous component (63%), turnor necrosis (36%) and adenocarcinoma component (0.6%) on histological mapping. Histologically, the tumor was composed of malignant osteoid tumor cells. Immunohistochemic al staining for cytokeratin was positive in the sarcomatous components. These findings favored the possible epithelial origin of the sarcomatous cells. Thus, the diagnosis confirmed a sarcomatoud dmlangiocarcinoma, with 2 osteosarcomatous components. After surgery, the pyrexia subsided, but early peritoneal and intrahepatic recurrence occurred 2 months postoperatively. He received systemic chemotherapy 6 times over 8 months, and partially responded. From our experienced the characteristics of this tumor have been found to be very aggressiveness, with poor prognosis.
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KEYWORD
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